Platelet-rich fibrin is a three-dimensional structure, the matrix of which is made of fibrin. In the areas of the three-dimensional fibrin network, there are high concentrations of non-activated, functional, intact platelets, white blood cells, as well as mesenchymal stem cells.

Together with fibrin, all the elements create a structure of matrix – a spatial structure which permanently and for a long period of time stimulates platelets to release growth factors, cytokines and effectively manages the migration of mesenchymal stem cells to the place of body injury.

The growth factors and stem cells released from the fibrin network space strongly stimulate the biological tissue renewal.

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Effects

A simple procedure of I-PRF obtaining uses only the physiological characteristics of blood. Blood is collected and centrifuged without any anticoagulants or artificial activators.

In methodology of the obtaining of platelet-rich fibrin for injections, it is very important to control time from the moment the blood has been collected, through centrifugation, until the moment the liquid platelet-rich fibrin has been applied during the treatment.

Liquid fibrin applied topically into tissues immediately fills the spaces from the inside. Thanks to the spatial structure being created in the tissues, platelets, white blood cells and stem cells which are in the network are slowly released from the fibrin matrix, and what begins is the process of tissue, cells and vessels renewal, as well as angiogenesis.

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Advantages

GUARANTEE OF SAFETY – liquid fibrin is obtained with the use of collection tubes, which have certificates of safety and required medical class II B.

THE FASTEST AUTOLOGOUS, NATURAL TREATMENT – methodology of the treatment assumes the obtaining of liquid platelet-rich fibrin in a short period of time.

SIMPLICITY OF THE OBTAINING OF PLATELET-RICH FIBRIN FOR INJECTIONS – comfort and convenience for the doctor because they can collect fibrin easily and obtain fibrin for treatment.

NATURAL, ECOLOGICAL TREATMENT – the patient will avoid allergic reactions. It is of utmost importance for patients. This information is vital for those who do not want to or do not like using substances of animal origin (creams in dermatology, gels and powders in dentistry and implantology). The treatment puts emphasis on the natural effect of tissue repair.

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Use

1. Aesthetic medicine

2. Dermatology

3. Orthopaedics

4. General and plastic surgery

5. Dentistry

6. Implantology

7. Ophthalmology

8. General and aesthetic gynaecology

9. Veterinary medicine

 

Contraindications

1. Blood diseases:

– platelet dysfunction syndromes

– critical thrombocytopenia

– fibrinogen deficiency

– haemodynamic instability

– septicaemia

1. Cancers

2. Chronic liver diseases

3. Acute and chronic infections

4. Pregnancy and lactation

5. Treatment with anticoagulants

6. The use of aspirin and other NSAIDs (non-steroidal anti-inflammatory drugs)

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